Compositions and delivery methods for treating dental infections, inflammation, sensitivity, and for use in dental restorations
AssigneesUniversity of Maryland, Baltimore, University of Maryland, College Park
InventorsRadi Masri, Didier Depireux
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Abstract
The present invention provides a method of treating a condition affecting a tooth or periodontium in a subject, comprising administering to the subject's tooth or periodontium a composition comprising biocompatible magnetic, magnetizable, or magnetically responsive agents; and applying an external magnetic field, wherein the magnetic, magnetizable, or magnetically responsive agents migrate to a desired location in response to the externally applied magnetic field, thereby treating a condition affecting the tooth or periodontium in the subject.
Claims9
A composition for treating a condition affecting a tooth or periodontium by delivery into dentinal tubules in a subject comprising biocompatible magnetic, magnetizable, or magnetically responsive agents, and an effective amount of a dental restorative/bonding material, wherein the magnetic, magnetizable, or magnetically responsive agents comprise a magnetic, magnetizable, or magnetically responsive core coated with a shell comprising a biocompatible polymer or polysaccharide matrix, wherein the magnetic, magnetizable, or magnetically responsive agents have a size of from 50 nm to 1500 nm so that they would be pulled by magnetic forces under an applied magnetic field to be delivered into the dentinal tubules of the subject, wherein the dental restorative/bonding material comprises a self-etch primer bonding agent, a self-etch adhesive bonding agent, or an etch and rinse bonding agent.
Dependencies are inferred from the claim text.