Chemical ablation and method of treatment for various diseases

A method for treating diabetes, the method comprising:

• inserting a first delivery catheter into a body lumen at a first treatment site in the small intestine, duodenum, or jejunum;
• infusing a chemical formulation from a formulation infusion lumen of the first delivery catheter to a tissue of the body lumen at the first treatment site, wherein the chemical formulation infused is effective to injure and/or damage the tissue at the first treatment site;
• withdrawing the first delivery catheter from the first treatment site;
• inserting a second delivery catheter that is the same or different as the first delivery catheter into a body lumen at a second treatment site in the small intestine, duodenum, or jejunum, wherein the second treatment site is a different treatment site than the first treatment site;
• infusing a chemical formulation from a formulation infusion lumen of the second delivery catheter to a tissue of the body lumen at the second treatment site, wherein the chemical formulation infused is effective to injure and/or damage the tissue at the second treatment site;
• withdrawing the second delivery catheter from the second treatment site;
• inserting a third delivery catheter into a body lumen at a third treatment site in the small intestine, duodenum, or jejunum, wherein the third treatment site is a different treatment site than the first and second treatment sites;
• infusing a chemical formulation from a formulation infusion lumen of the third delivery catheter to a tissue of the body lumen at the third treatment site, wherein the chemical formulation infused is effective to injure and/or damage the tissue at the third treatment site;
• and
• withdrawing the third delivery catheter from the third treatment site;
• wherein the injury and/or damage to the tissue at the first treatment site, at the second treatment site, and at the third treatment site is effective to have a benefit of relieving symptoms comprising reduction of HbA1c (A1c) and glucose level.

A method for treating diabetes and obesity, the method comprising:

• inserting a first delivery catheter into a body lumen at a first treatment site in the small intestine, duodenum, or jejunum;
• infusing a chemical formulation from a formulation infusion lumen of the first delivery catheter to a tissue of the body lumen at the first treatment site, wherein the chemical formulation infused is effective to injure and/or damage the tissue at the first treatment site;
• withdrawing the first delivery catheter from the first treatment site;
• inserting a second delivery catheter into a body lumen at a second treatment site in the small intestine, duodenum, or jejunum, wherein the second treatment site is a different treatment site than the first treatment site;
• and
• infusing a chemical formulation from a formulation infusion lumen of the second delivery catheter to a tissue of the body lumen at the second treatment site, wherein the chemical formulation infused is effective to injure and/or damage the tissue at the second treatment site;
• and
• withdrawing the second delivery catheter from the second treatment site;
• wherein the injury and/or damage to the tissue at the first treatment site and to the tissue at the second treatment site is effective to have a benefit of relieving symptoms comprising reduction of HbA1c (A1c), glucose level, and body weight.