Reversible bioadhesive

A composition of matter useful as an adhesive, comprising:

• a bistable adhesive polymer comprising:
• one or more polymer backbones;
• side-chains attached to each of the polymer backbones;
• one or more transition temperatures between a crystalline state and an amorphous state, wherein:
• the one or more transition temperatures are such that the polymer transitions from the crystalline state to the amorphous state upon physical contact with a substrate having a temperature higher than the transition temperature of the bistable adhesive polymer;
• and
• the polymer adheres or attaches to the substrate with conformity in the amorphous state and can be peeled from the substrate when cooled below the transition temperature of the bistable adhesive polymer to the crystalline state, wherein:
• the polymer comprises a copolymer including a combination or mixture of a first component, a second component, a third component, wherein:
• the first component has a first transition temperature below the temperature of the substrate,
• the second component has a second transition temperature greater than the temperature of the substrate,
• the third component has a storage modulus tailoring a polymer storage modulus of the copolymer such that the storage modulus of the third component and the polymer storage modulus are below 2 MPa at the temperature of the substrate, and
• the first transition temperature and the second transition temperature are such that the copolymer has the one or more transition temperatures above the first transition temperature but below the temperature of the substrate biological tissue.