Oral product with nicotine and ion pairing agent
AssigneeNicoventures Trading Limited
InventorsThomas H. Poole, Christopher Keller, Brian Michael Keyser, Serban C. Moldoveanu
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AssigneeNicoventures Trading Limited
InventorsThomas H. Poole, Christopher Keller, Brian Michael Keyser, Serban C. Moldoveanu
Estimating the term…
The disclosure provides compositions configured for oral use, the compositions including at least one filler, water, a basic amine, and an organic acid, an alkali metal salt of an organic acid, or a combination thereof, wherein the organic acid has a logP value of from about 1.4 to about 8.0. At least a portion of the basic amine is associated with at least a portion of the organic acid or the alkali metal salt thereof. The association is in the form of a basic amine-organic acid salt, an ion pair between the basic amine and a conjugate base of the organic acid, or a combination of both. Further provided are methods for stabilizing a composition configured for oral use and for enhancing a predicted buccal absorption of a composition configured for oral use.
A composition configured for oral use, the composition comprising:
A method of enhancing the stability of a composition configured for oral use, the stabilized composition comprising:
A method of enhancing a predicted oral mucosal absorption of a basic amine from a composition configured for oral use, the composition comprising:
Dependencies are inferred from the claim text.