Methods of treating RBP4 related diseases with triazolopyridines

A method of treating a metabolic disease or disorder in a subject in need thereof, the method comprising administering to the subject a composition comprising a therapeutically effective amount of a compound of Formula (I), or a pharmaceutically acceptable salt thereof

• wherein:
• each R1 is independently halogen, haloalkyl, or alkyl;
• R2 is H, OH, or halogen;
• p is 0, 1, 2, 3, 4, or 5;
• and
• A has the structure:
• wherein:
• α, β, χ, and δ are each independently absent or present, and when present each is a bond;
• X is N;
• Z1 is S, O, or N;
• Z2 is S, O, N, or NR3;
• R3 is H, C1-C4 alkyl, or oxetane;
• and
• B is a substituted or unsubstituted fused 5-, 6-, or 7-membered ring structure, wherein the metabolic disease or disorder is liver fibrosis, liver cancer, or liver cirrhosis.