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US 12,714,679 B2Granted
Fullerenes to treat diseases and conditions
AssigneeThe Cleveland Clinic Foundation
InventorsVijay Krishna, Christopher Hine
Life of this patent
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Abstract
Provided herein are compositions, systems, kits, and methods for treating a subject with a disease or condition by administering a composition comprising fullerenes to the subject such that H2S is generated in the subject. In certain embodiments, the disease or condition is associated with inflammation and/or below normal H2S levels. In certain embodiments, the fullerenes are polyhydroxy fullerenes (PHFs).
Claims2
A method comprising:
- contacting a thiol-containing compound with a composition comprising C60 polyhydroxy-fullerenes in vitro such that H2S is generated.
Dependencies are inferred from the claim text.