Oral care compositions with phosphopeptides for use against dental hypersensitivity and/or xerostomia
OwnerRichard Willsoninventor
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Abstract
The present invention relates to compositions for use in oral care and various methods of their use. In particular, it relates to compositions comprising phosphoproteins and their use in the treatment and prevention of dentine hypersensitivity and the treatment and prevention of xerostomia. Preferred compositions comprise osteopontin and derivatives thereof.
Claims21
A method of treatment to reduce dental hypersensitivity in a subject in need thereof, wherein the method comprises administering to the subject's oral cavity a therapeutically effective amount of a composition comprising a phosphopeptide, and wherein further the composition does not comprise additional phosphate or an additional source of phosphate.
A method of treatment of xerostomia in a subject in need thereof, wherein the method comprises administering to the subject's oral cavity a therapeutically effective amount of a composition comprising a phosphopeptide, and wherein further the composition does not comprise additional phosphate or an additional source of phosphate.
A method of treatment of demineralisation of an oral surface, dental caries and/or candidiasis infection in a subject having xerostomia, wherein the method comprises administering to the subject's oral cavity a therapeutically effective amount of a composition comprising a phosphopeptide, and wherein further the composition does not comprise additional phosphate or an additional source of phosphate.
A method of maintaining enamel mineral density in a subject having hypersensitivity and/or xerostomia, wherein the method comprises administering to the subject's oral cavity a therapeutically effective amount of a composition comprising a phosphopeptide, and wherein further the composition does not comprise additional phosphate or an additional source of phosphate.
Dependencies are inferred from the claim text.