Analyte sensor and method for manufacturing an analyte sensor
AssigneeRoche Diabetes Care, Inc.
InventorsKirill Sliozberg, Alexander Steck
Life of this patent
Estimating the term…
Abstract
The disclosure relates to an analyte sensor comprising a substrate, at least one working electrode, at least one second electrode and a membrane, wherein the membrane is located on top of the second electrode, and the second electrode has at least one first silver layer and at least one second silver layer which at least partially overlap with one another and have different compositions. The sensor includes at least one exposed area of the first silver layer disposed on the exterior of the sensor to provide for direct contact with body fluid when implanted. The disclosure further relates to a process for manufacturing an analyte sensor.
Claims15
An analyte sensor comprising
- a substrate comprising a first side and a second side;
- at least one working electrode positioned on the first side of the substrate, the at least one working electrode comprising:
- at least one electrically conductive material and
- at least one enzyme;
- at least one second electrode positioned on the second side of the substrate, the at least one second electrode comprising at least one first silver layer and at least one second silver layer, wherein the at least one second silver layer at least partially overlaps with the at least one first silver layer, wherein the at least one first and at least one second silver layers comprise different compositions, wherein the at least one first and at least one second silver layers comprise AgCl and wherein the at least one first silver layer includes a lower weight % of AgCl than a weight % of AgCl of the at least one second silver layer based on a total weight of the at least one first silver layer and a total weight of the at least one second silver layer;
- and
- a membrane comprising a polymer composition which comprises a hydrophobic polymer, wherein the membrane is located on top of the at least one second electrode,
- wherein the analyte sensor comprises at least one exposed area of the at least one first silver layer, said at least one exposed area being disposed on an exterior of the analyte sensor and configured to be in direct contact with body fluid when the analyte sensor is implanted in a user.
A method for manufacturing an analyte sensor, the method comprising the steps:
- a) providing a raw substrate which comprises a first side and a second side;
- b) preparing a working electrode region on the first side of the raw substrate, the preparing of the working electrode region comprising the steps:
- b1) applying an electrically conductive material to the first side of the raw substrate,
- b2) applying a sensing material comprising at least one enzyme at least partially on the electrically conductive material;
- c) preparing a second electrode region on the second side of the raw substrate, the preparing of the second electrode region comprising the steps:
- c1) applying a first silver composition to form a first silver composition region on the second side of the raw substrate,
- c2) applying a second silver composition as a plurality of separated regions over the first silver composition region such that the second silver composition regions partially overlap with the first silver composition region, wherein the second silver composition has a different composition than the first silver composition, wherein the first silver composition and the second silver composition each comprise AgCl and the first silver composition includes a lower weight % of AgCl than the second silver composition based on a total weight of the first silver composition and a total weight of the second silver composition;
- d) applying a polymer composition on top of the second electrode region, to obtain a membrane, wherein the polymer composition comprises a hydrophobic polymer;
- and
- e) cutting the raw substrate, the working electrode region, the second electrode region and the membrane, wherein only the first silver composition region of the second electrode region is cut such that the first silver composition region comprises at least one exposed area configured to be in direct contact with body fluid when the analyte sensor is implanted in a user.
Dependencies are inferred from the claim text.