Reducing malaria transmission
AssigneeGlaxoSmithKline Intellectual Property Development Limited
InventorsAlfonso Mendoza Losana, Janneth Rodrigues
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Abstract
The present invention relates to a composition comprising bacteria of the Delftia genus, specifically a composition comprising Delftia tsuruhatensis as well as the bacteria itself for use in the prevention of malaria transmission and methods of using the compositions for reducing malaria and/or malaria parasite transmission.
Claims6
A method of suppressing Plasmodium falciparum malaria parasite transmission comprising administering to one or more adult Anopheles mosquitoes in a colony a composition comprising Delftia tsuruhatensis bacteria in pure form, thereby suppressing the Plasmodium falciparum malaria parasite transmission in the colony.
A method of inhibiting ookinetes and oocysts of Plasmodium falciparum in Anopheles mosquito midgut comprising administering to one or more adult Anopheles mosquitoes in a colony a composition comprising Delftia tsuruhatensis bacteria in pure form, thereby inhibiting the ookinetes and oocysts of Plasmodium falciparum in adult Anopheles mosquitoes' midgut in the colony.
Dependencies are inferred from the claim text.