Back to results
US 12,709,740 B2Granted
Method for hypothermic transport of biological samples
AssigneeParagonix Technologies, Inc.
InventorsDanny Macari, Matthew Whitney, Samantha Estrella, William Lucas Churchill
Life of this patent
Estimating the term…
Abstract
A method for transporting a biological sample at hypothermic temperatures. The container can be cooled using phase change material and pump fluid through the sample. The fluid can pump through the system at a rate independent of the parameters of the biological sample. A valve can control the rate of flow of the fluid into the biological sample.
Claims20
A system for preservation of a biological sample comprising:
- a transport container configured to contain a biological sample;
- a pump configured to pump preservation fluid from the transport container to an inlet of a fluid circuit;
- a flow regulator valve in fluid communication with the inlet, the flow regulator valve configured to regulate a flow rate into the biological sample based on a biological sample parameter, wherein the flow regulator valve is configured to release fluid into the transport container at a rate based on the biological sample parameter;
- and
- a biological sample adapter in fluid communication with the inlet of the fluid circuit and configured to couple with the biological sample,
- wherein the biological sample parameter comprises at least one of vessel resistance, biological sample temperature, or flow rate through the biological sample,
- wherein the fluid circuit comprises fluid in the transport container and fluid flowing from the inlet to the biological sample adapter when the biological sample is contained in the transport container and coupled with the biological sample adapter, and
- wherein the fluid circuit is configured to form a closed fluid system when the biological sample is contained in the transport container and coupled with the biological sample adapter.
5 more elements
A system for preservation of a biological sample comprising:
- a transport container configured to contain a biological sample;
- a pump configured to pump preservation fluid through a fluid circuit to a flow regulator valve, the flow regulator valve configured to regulate a flow rate into the biological sample based on a biological sample parameter, wherein the flow regulator valve is configured to release fluid into the transport container at a rate based on the biological sample parameter;
- and
- a biological sample adapter in fluid communication with the flow regulator valve and configured to couple with the biological sample,
- wherein the biological sample parameter comprises at least one of vessel resistance, biological sample temperature, flow rate through the biological sample, or organ pressure,
- wherein the fluid circuit comprises fluid in the transport container and fluid flowing from the transport container to the biological sample adapter when the biological sample is contained in the transport container and coupled with the biological sample adapter, and
- wherein the transport container and the fluid circuit are configured to form a closed fluid system when the biological sample is contained in the transport container and coupled with the biological sample adapter.
4 more elements
Dependencies are inferred from the claim text.