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US 12,708,758 B2Granted
Distensible knitted wire mesh for a cardiac sleeve
AssigneeThe Regents of the University of California
InventorsArash Kheradvar, Gregory S. Kelley
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Abstract
Heart failure (HF) is a global pandemic affecting at least 26 million people worldwide. Thus, methods and devices that reduce the clinical and economic burden of HF are critical. The present invention features an adjustable cardiac sleeve comprising a basal ring structure and an apical hub couple together, wherein the basal ring structure comprises a plurality of interconnected loops made from a distensible wire.
Claims19
An adjustable cardiac sleeve (100) comprising:
- a) a basal ring structure (130) comprising a plurality of interconnected loops interlaced with one another, wherein a first loop end (131) is connected to a second loop end (132) of the plurality of loops to form a ring;
- b) an apical hub (120) coupled to the basal ring structure (130) by a plurality of non-overlapping, helically-arranged fibers;
- and
- c) an actuator (140) operably connected to the apical hub (120), wherein the actuator (140) is configured to compress a heart by actively twisting the plurality of non-overlapping, helically-arranged fibers:
- wherein the adjustable cardiac sleeve (100) is attached to a surface of the heart via an anchoring mechanism.
2 more elements
A method of treating heart failure in a subject in need thereof, the method comprising:
- a) obtaining a cardiac sleeve (100) comprising:
- i) a basal ring structure (130) comprising a plurality of interconnected loops interlaced with one another, wherein a first loop end (131) is connected to a second loop end (132) of the plurality of interconnected loops to form a ring:
- ii) an apical hub (120) coupled to the basal ring structure (130) by a plurality of non-overlapping, helically-arranged fibers;
- and
- iii) an actuator (140) operably connected to the apical hub (120);
- b) externally wrapping the cardiac sleeve (100) over an epicardium of a native, intact heart of the subject, and
- c) attaching the cardiac sleeve to the epicardium of the native, intact heart via an anchoring mechanism,
- d) operating the actuator (140) to cycle the cardiac sleeve (100) between a diastolic position and a systolic position.
5 more elements
Dependencies are inferred from the claim text.