Fully implanted aphereter/dialyzers for intracorporeal blood purification
OwnerDavid S. Goldsmithinventor
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OwnerDavid S. Goldsmithinventor
Estimating the term…
A fully implantable intracorporeal blood purifier for patients with impaired, missing, or normal kidneys overwhelmed by a myeloproliferative disorder such as polycythemia vera, essential thrombocythemia, primary myelofibrosis, or chronic myelogenous leukemia. Functioning continuously or intermittently around the clock, the patient is spared the need to visit the clinic as frequently for treatment, and less severe renal dysfunction may allow the intervals between visits to be considerably extended if not eliminated. The intracorporeal blood purifier represents the extractive or negative component in a prosthetic disorder response system of which the positive component detects the need for and releases medication such as tyrosine-kinase inhibitors—imatinib, and interferon alfa-2b, and cooperates with the purifier to accomplish kidney functions not simply extractive, such as releasing hormones, calcitriol, sodium, and potassium into the blood, maintaining electrolyte, acid-base, and fluid balance, and furnishing small molecule amino acids and glucose by directly targeting the gut.
An intracorporeal blood purifier for implantation configured to compensate for an inadequacy in renal function due to any disease and supplement normal renal function in the treatment of a myeloproliferative disease, said blood purifier comprising a succession of disease-related analyte separation magnets configured to be placed along and in perivascular relation to a substrate vessel, wherein the separation magnets are configured to extract and deliver said disease-related analytes into the urinary bladder, said disease-related analytes having been rendered magnetically susceptible by bonding to superparamagnetic carriers, wherein said blood purifier further comprises extractive windows configured to separate the blood flowing through the substrate vessel and the extraction magnets, said extractive windows including semipermeable membranes and resilient one-way slit valves.
An implanted automatic prosthetic disorder response system comprising:
Dependencies are inferred from the claim text.