Nanometric pharmaceutical composition in the form of liposomes or nanoemulsion containing specific sequences of interference RNA
OwnerElizandra Braganhol, Ana Maria Oliveira Battastini +6inventors
InventorsElizandra Braganhol, Ana Maria Oliveira Battastini, Helder Teixeira, Marco Antonio Stefani, Fernanda Bruxel, Roselia Maria Spanevello, Fernanda Cardoso Teixeira, Juliana Hofstatter Azambuja
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Abstract
A nanometric pharmaceutical composition in the form of liposomes or a nanoemulsion containing interference RNA strands comprising one or more of the following specific siRNA sequences: SEQ ID NO: 1; SEQ ID NO: 2; or SEQ ID NO: 3.
Claims20
A nanometric pharmaceutical composition in the form of liposomes or a nanoemulsion containing interference RNA strands comprising one or more of the following specific siRNA sequences:
- SEQ ID NO:
- 1;
- SEQ ID NO:
- 2;
- or
- SEQ ID NO:
- 3.
A process for manufacturing a drug, wherein the process comprises forming a cationic nanometric lipid formulation and associating therewith an siRNA consisting of SEQ ID NO:
- 3 under conditions effective to form an electrostatic complex for treating a disease characterized by elevated CD73 expression.
Dependencies are inferred from the claim text.