Methods of making targeted vesicles, and compositions made thereby
AssigneeUniversity of Georgia Research Foundation, Inc.
InventorsArthur Roberts, Mandi Murph, Sudeepti Kuppa, Pragati Jain
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Abstract
Functionalized lipid vesicles having a lipid membrane and a functional element, and methods of making them are provided. The methods of making the vesicles typically include mixing lipid vesicles formed of one or more lipids with one or more lipid conjugates and dialyzing the mixture for an effective amount of time and under conditions suitable for the lipid conjugate to insert into the membrane of lipid vesicles and form functionalized lipid vesicles that include the lipid conjugate as a functional element.
Claims20
A method of making functionalized lipid vesicles comprising a lipid membrane, the method comprising mixing in the presence of detergent, lipid vesicles comprising one or more lipids with one or more types of lipid conjugates, each type of lipid conjugate comprising a lipid component and a functional element
- and dialyzing the mixture for an effective amount of time for the lipid conjugate(s) to insert into the lipid vesicles and form functionalized lipid vesicles.
Dependencies are inferred from the claim text.