Therapeutic systems, devices, and compositions with wound healing and tissue regenerative properties, uses thereof, and corresponding methods

A system for healing soft and/or hard tissue damage subsequent to an acute or chronic injury to an individual, the system comprising:

• a power source;
• and
• an energy source coupled to the power source, the energy source comprising a portable housing, a controller, a circuit board, and one or more emitters comprising one or more electrodes,
• the housing configured to house the controller, circuit board, and the one or more emitters,
• the housing comprising a contoured gripping handle, and a head portion,
• the contoured gripping handle configured to house the controller and the circuit board, and the head portion comprising the one or more emitters,
• the one or more emitters being arranged on an outer surface of the head portion and configured to be oriented toward the tissue damage;
• and
• the controller configured to control the circuit board to cause the one or more emitters to emit energy at a frequency of 1 Hz to 150 kHz;
• wherein:
• the housing and the one or more emitters of the energy source are configured to be placed over, but not in contact with, the tissue damage such that the energy is directed from the one or more emitters away from the housing and toward the tissue damage across an air gap or a gel interface between the one or more emitters and the tissue damage, and an external electron flow from the one or more emitters of the energy source to the tissue damage causes healing at the acute or chronic injury;
• the energy comprises electrons configured to be transferred into damaged tissue to heal the soft and/or hard tissue damage;
• and
• hard and/or soft tissue comprises tissue from ectodermal, endodermal, and/or mesodermal origin that includes vasculature;
• skin;
• muscle;
• nerves;
• and/or bone.