Dendritic cell vaccination sequential to chemotherapy

A method of treatment of ovarian cancer in a patient comprising administering to the patient a chemotherapy and a dendritic cell vaccine, wherein the chemotherapy consists of a combination treatment of paclitaxel and carboplatin and wherein the dendritic cell vaccine is administered to the patient after completion of the chemotherapy,

• Wherein:
• the dendritic cells are loaded ex vivo with whole ovarian tumor cells killed by high hydrostatic pressure,
• from 5 to 30 doses of dendritic cell vaccines are administered, and
• the cancer is Stage II-IV newly diagnosed ovarian cancer prior to the administration of first dose of the chemotherapy,
• wherein the first dose of the dendritic cell vaccine is administered within two months after administration of last dose of the chemotherapy.