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US 12,708,616 B2Granted
Compositions and methods of treating age-related retinal dysfunction
AssigneeThe Regents of the University of California
InventorsJennings Luu, Krzysztof Palczewski
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Abstract
A method of treating and/or preventing age-related retinal dysfunction in a subject in need thereof includes administering to the subject a therapeutically effective amount of an agent that attenuates stress-induced chromatin remodeling associated with the age-related retinal dysfunction.
Claims8
A method of treating age-related macular degeneration in a subject in need thereof, the method comprising:
- administering to the subject therapeutically effective amounts of agents that attenuate stress-induced chromatin remodeling associated with age-related macular degeneration, wherein the agents comprise a histone deacetylase 11 (HDAC11) inhibitor and a suppressor of variegation 3-9 homolog 2 (SUV39H2) inhibitor.
Dependencies are inferred from the claim text.