Compositions for disrupting biofilm formation and for treating biofilm-related disorders
AssigneeAHV International B.V.
InventorsGerrit Jan Streefland, Jan De Rooij
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Abstract
The disclosure relates to thiosulfur containing compositions, in particular propyl-propane thiosulfonate (PTSO) and propyl-propane-thiosulfinate (PTS). Such compositions are useful for treating infection and reducing or degrading biofilms both in vivo and in vitro. In particular, such compositions are useful in the treatment of biofilm-related disorders, including but not limited to mastitis, digital dermatitis, and chronic wound infections.
Claims14
A method for treating a biofilm-related infection in an individual, said method comprising administering to an individual in need thereof a composition comprising a compound according to formula I
- wherein R1 and R2 are independently selected from optionally substituted linear or branched alkyl, optionally substituted linear or branched alkenyl, optionally substituted linear or branched alkynyl, optionally substituted aryl, optionally substituted cycloalkyl, optionally substituted heterocycloalkyl.
Dependencies are inferred from the claim text.