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US 12,708,606 B2Granted
Lithium fluoride nanoparticles for the protection of chondrocytes in osteoarthritis
AssigneeUniversity of Georgia Research Foundation, Inc.
InventorJin Xie
Life of this patent
Estimating the term…
Abstract
Disclosed are particles comprising lithium salts and methods for their use in treating inflammatory conditions.
Claims15
A method of treating an inflammatory disease in a subject comprising administering to the subject a particle comprising a lithium salt core and an encapsulating silica shell;
- wherein the lithium salt core is not a lithium chloride (LiCl) salt core.
A method of treating osteoarthritis in a subject comprising administering to the subject a particle comprising a lithium fluoride (LiF) salt core and an encapsulating silica shell;
- wherein the LiF salt core further comprises a hyaluronic acid eluting matrix that releases the LiF salt from the matrix over a sustained rate.
Dependencies are inferred from the claim text.