Prosthetic heart valve devices, prosthetic mitral valves and associated system and methods

A prosthetic heart valve device for treating a native valve having a native annulus and native leaflets, the prosthetic heart valve device including a radially compressed configuration and a radially expanded configuration, the prosthetic heart valve device comprising:

• a valve support inner stent expandable from a low-profile configuration for delivery to an expanded configuration for implantation at the native valve;
• a prosthetic valve mounted to the valve support inner stent and adapted to allow blood flow in a downstream direction and to block blood flow in an upstream direction;
• and
• an anchoring member outer stent including a first end attached to the valve support and a second end spaced radially from the valve support inner stent such that a radial gap is disposed between the anchoring member outer stent and the valve support inner stent with the prosthetic heart valve device in the radially expanded configuration;
• wherein the anchoring member outer stent includes a plurality of rows of cells;
• wherein a first row of cells of the plurality of rows of cells disposed adjacent the first end of the anchoring member outer stent includes cells having a first cell size;
• wherein a second row of cells of the plurality of rows of cells includes cells having a diamond shape and a second cell size smaller than the first cell size;
• wherein the second row of cells is disposed spaced apart from the first end such that the first row of cells is disposed between the second row of cells and the first end;
• wherein a third row of cells of the plurality of rows of cells includes cells having a diamond shape and a third cell size that is smaller than the first cell size;
• and
• wherein the second row of cells is disposed between the third row of cells and the first row of cells.