Systems and methods for selective occlusion of the peripheral venous vasculature to unload the heart
AssigneeABIOMED, Inc.
InventorChristopher Korkuch
Life of this patent
Estimating the term…
Abstract
Systems and methods for intermittently occluding a patient's venous vasculature to unload the heart while increasing cardiac output and improving perfusion to the patient's heart is provided. The system may include first and second balloon catheters that may be selectively actuated to intermittently occlude first and second veins for increasing venous vascular resistance in the patient's lower and upper extremities, respectively, to thereby selectively reduce arterial blood flow to the lower and upper extremities, while maintaining arterial vascular resistance of the patient's heart and central organs and increasing perfusion to the patient's heart and central organs.
Claims28
A system for unloading a heart of a patient to improve cardiac performance, the system comprising:
- a first flow limiting element configured to be selectively actuated to occlude a superior vena cava (SVC) in fluid communication with a first extremity of the patient;
- a second flow limiting element configured to be selectively actuated to occlude an inferior vena cava (IVC) in fluid communication with a second extremity of the patient;
- a controller operatively coupled to the first and second flow limiting elements, the controller configured to cause the first and/or second flow limiting elements to expand according to a predetermined actuation regimen to selectively occlude the SVC and/or IVC to reduce cardiac preload and increase mean arterial pressure to thereby selectively increase arterial vascular resistance of the patient's extremities, while maintaining arterial vascular resistance of the patient's heart and end organs and increasing perfusion to the patient's heart and end organs.
A system for unloading a heart of a patient to improve cardiac performance, the system comprising:
- a first flow limiting element configured to be selectively actuated to occlude a first vein in fluid communication with a first extremity of the patient;
- a second flow limiting element configured to be selectively actuated to occlude a second vein in fluid communication with a second extremity of the patient;
- a controller operatively coupled to the first and second flow limiting elements, the controller configured to cause the first and/or second flow limiting elements to expand according to a predetermined actuation regimen to selectively occlude the first and/or second veins to reduce cardiac preload and increase mean arterial pressure to thereby selectively increase arterial vascular resistance of the patient's extremities, while maintaining arterial vascular resistance of the patient's heart and end organs and increasing perfusion to the patient's heart and end organs,
- wherein each occlusion period during a treatment session is at least one minute.
A method for unloading a heart of a patient to improve cardiac performance, the method comprising:
- positioning a first flow limiting element within a superior vena cava (SVC) in fluid communication with a first extremity of the patient;
- positioning a second flow limiting element within an inferior vena cava (IVC) in fluid communication with a second extremity of the patient;
- and
- causing the first and/or second flow limiting elements to expand according to a predetermined actuation regimen to selectively occlude the SVC and/or IVC to reduce cardiac preload and increase mean arterial pressure to thereby selectively increase arterial vascular resistance of the patient's extremities, while maintaining arterial vascular resistance of the patient's heart and end organs and increasing perfusion to the patient's heart and end organs.
Dependencies are inferred from the claim text.