Production of vanillin-glucoside from lignin-derived carbon
AssigneeNorthwestern University
InventorsBradley W. Biggs, Keith E.J. Tyo
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Abstract
The present disclosure provides engineered bacteria for producing vanillin.
Claims21
An engineered Acinetobacter baylyi that is capable of production of vanillin-glucoside from carbon sources derived from lignin and that comprises a genome that is modified, wherein a catechol O-methyltransferase (COMT) gene and a UDP-glycosyltransferase (UGT) gene are each independently integrated into the genome of the engineered Acinetobacter baylyi, and wherein at least ten genes selected from ACIAD1725, ACIAD1430, ACIAD1429, ACIAD0503, ACIAD1577, ACIAD1578, ACIAD1009, ACIAD1716, ACIAD2018, ACIAD1879, ACIAD3339, ACIAD2774, ACIAD3612, ACIAD2015, ACIAD2929, ACIAD1743, ACIAD2542, ACIAD3616, ACIAD1950, and ACIAD3642 have been knocked out.
Dependencies are inferred from the claim text.