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US 12,703,739 B2Granted
Human antibodies to rift valley fever virus
AssigneeVanderbilt University
InventorJames E. Crowe, Jr.
Life of this patent
Estimating the term…
Abstract
The present disclosure is directed to antibodies binding to and neutralizing Rift Valley Fever Virus and methods for use thereof.
Claims11
A method of treating a subject infected with Rift Valley Fever Virus or reducing the likelihood of infection of a subject at risk of contracting Rift Valley Fever Virus, comprising delivering to said subject an antibody or antibody fragment comprising (i) heavy chain CDR1-3 comprising SEQ ID NO:
- 346, SEQ ID NO:
- 347 and SEQ ID NO:
- 348, respectively, and light chain CDR1-3 comprising SEQ ID NO:
- 592, SEQ ID NO:
- 593 and SEQ ID NO:
- 594, respectively;
- (ii) heavy chain CDR1-3 comprising SEQ ID NO:
- 424, SEQ ID NO:
- 425 and SEQ ID NO:
- 426, respectively, and light chain CDR1-3 comprising SEQ ID NO:
- 670, SEQ ID NO:
- 671 and SEQ ID NO:
- 672, respectively;
- or (iii) heavy chain CDR1-3 comprising SEQ ID NO:
- 532, SEQ ID NO:
- 533 and SEQ ID NO:
- 534, respectively, and light chain CDR1-3 comprising SEQ ID NO:
- 775, SEQ ID NO:
- 776 and SEQ ID NO:
- 777, respectively.
17 more elements
Dependencies are inferred from the claim text.