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US 12,703,690 B2Granted
Process for preparing alkyl-4-oxotetrahydrofuran-2-carboxylate
AssigneeBayer Aktiengesellschaft
InventorsAnton Lishchynskyi, Carlos Moriana Herraiz, Günter Hömberger, Mark James Ford
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Abstract
The present invention relates to a novel method for preparing alkyl 4-oxotetrahydrofuran-2-carboxylate (I)
Claims20
A method for preparing a compound of general formula (I)
- in which
- R1 is (C1-C4) alkyl,
- the method comprising:
- reacting a compound of general formula (II)
- in which
- R2 is (C1-C4) alkyl,
- with a compound of general formula (III)
- in which R1 is as defined above,
- in the presence of MO—Z in an alcohol Z—OH,
- in which
- M is an alkali metal ion and
- Z is (C1-C4) alkyl, not including t-butyl;
- forming, in a cyclization reaction, a cyclization product of general formula (IV)
- in which R1 is as defined for formula (I);
- and
- reacting, under non-hydrolytic conditions, the cyclization products in a dealkoxycarbonylation reaction to form the compound of general formula (I).
13 more elements
Dependencies are inferred from the claim text.