4-Methoxy-2-phenethyl isoindoline-1-one derivative and composition for treating neurological diseases, comprising same
AssigneesCng Bio Co., Ltd., Chungbuk National University Industry-Academic Cooperation Foundation, Gachon University of Industry-Academic Cooperation Foundation
InventorsJaekyung Jung, Mi Kyeong Lee, Dae Hee Lee, Jae Kang Lee, Sun Yeou Kim, Da Hye Yoon, Seong Min Hong
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Abstract
The present invention relates to: a novel 4-methoxy-2-phenethyl isoindolin-1-one derivative compound having the ability to promote the increase of nerve growth factor, the ability to promote the growth of nerve cells, and antineuritic activity; and a composition for preventing, improving and treating neurological diseases, comprising the same.
Claims9
A compound represented by Formula 9 below or a pharmaceutically acceptable salt thereof:
- in the formula,
- R1 is hydrogen, alkyl, alkenyl, alkynyl, hydroxy, alkoxy, hydroxyalkyl, alkoxyalkyl, or —N(Ra)(Rb);
- R2, R3, R4, Ra and Rb are each independently hydrogen or alkyl;
- and
- X is a single bond or a double bond.
A compound selected from the group consisting of compounds of the following formulas or a pharmaceutically acceptable salt thereof:
Dependencies are inferred from the claim text.