Methods for identification, assessment, prevention, and treatment of metabolic disorders using SLIT2
AssigneeDana-Farber Cancer Institute, Inc.
InventorsBruce M. Spiegelman, Katrin J. Svensson
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Abstract
The present invention relates to methods for identifying, assessing, preventing, and treating metabolic disorders and modulating metabolic processes using Slit2.
Claims10
A method for detecting an agent that modulates Slit2 expression and/or activity for increasing a metabolic response in a subject, comprising detecting whether expression and/or activity of Slit2-C is significantly lower in a first sample from the subject prior to contact with the agent than for at least one subsequent sample from the subject after contact with the agent by contacting the first sample with an antibody that detects Slit2-C, and detecting association of Slit2-C and the antibody that detects Slit2-C.
Dependencies are inferred from the claim text.