Antimicrobial therapy
AssigneeThe Regents of the University of California
InventorsRichard L. Gallo, Teruaki Nakatsuji, Kate Worthing, Alan O. O'Neill
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Abstract
This disclosure provides a synthesized version of S. felis C4 antimicrobial peptide as a topical antibiotic. S. felis C4 can be used as a probiotic strain of skin bacteria that can be transplanted onto the diseased skin of dogs, cats and dairy cows to outcompete and kill pathogenic bacteria that are causing infections such as bacterial pyoderma and mastitis.
Claims9
A composition comprising a peptide having the sequence of SEQ ID NO:3, or a sequence that includes 1 to 5 amino acid substitutions to SEQ ID NO:3, and at least one peptide selected from the group consisting of SEQ ID NO:4, 5 and 6, a pharmaceutically acceptable carrier for formulation as a lotion, ointment cream, powder, unguent, oil or spray, and wherein the composition inhibits or kills S. aureas and/or S. pseudintermidius.
Dependencies are inferred from the claim text.