Nicotinic acid derivative A with anti-inflammation and anti-platelet aggregation activities, and use thereof
AssigneeChongqing Academy of Chinese Materia Medica
InventorsYong Yang, Yanlei Guo, Dajian Yang
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Abstract
The present disclosure provides a nicotinic acid derivative A with an anti-inflammation activity. The nicotinic acid derivative A has a general structural formula shown in formula (I), where R1 and R2 are different substitution sites of a main chain, and R1′ and R2′ are different substitution sites of a side chain. In the present disclosure, the nicotinic acid derivative A has desirable anti-inflammation, anti-tumor, and anti-platelet aggregation activities, and strong selectivity, and shows a remarkable clinical application value.
Claims1
A method for treating an autoimmune disease, comprising administrating or applying a nicotinic acid derivative A with an immunosuppressive activity to a subject in need, wherein the autoimmune disease is rheumatoid arthritis;
- and the nicotinic acid derivative A has a structural formula as follows:
Dependencies are inferred from the claim text.