Method of treating cystic fibrosis airway disease
AssigneeUniversity of Iowa Research Foundation
InventorsJoseph Zabner, Michael J. Welsh, David A. Stoltz, Mahmoud Abou Alaiwa
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Abstract
In certain embodiments, the present invention provides a method of increasing liquid pH on airway surface of a tissue in a patient in need thereof comprising administering an effective amount of a therapeutic composition comprising tromethamine to the patient.
Claims13
A method of treating an airway infection in a mammal in need thereof by administering a therapeutically effective amount of a therapeutic composition consisting of tromethamine, an effective amount of hypertonic saline and an effective amount of NaHCO3.
A method of treating an airway infection in a mammal in need thereof by administering a therapeutically effective amount of a therapeutic composition, wherein the therapeutic composition consists of tromethamine, tobramycin, and one or more agents selected from the group consisting of an effective amount of hypertonic saline and an effective amount of NaHCO3.
Dependencies are inferred from the claim text.