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US 12,702,641 B2Granted
System for providing birth control
AssigneeThe Population Council, Inc.
InventorBruce Variano
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to a vaginal system that prevents pregnancy comprised of segesterone acetate and ethinyl estradiol and is configured for thirteen 28-day product-use cycles.
Claims18
A process for preparing a reusable vaginal ring system for preventing pregnancy configured to release an approximate average of 0.15 mg/day of segesterone acetate and an approximate average of 0.013 mg/day of ethinyl estradiol for up to 13 cycles of 21 days each, the process comprising:
- a) adding an uncured addition-cure silicone elastomer having a platinum concentration of approximately 3 ppm to approximately 10 ppm and a hydride/vinyl ratio from approximately 1:1 to approximately 1.3:1 to a mold configured to provide a ring body comprising two channels adapted to receive first and second drug-containing cores;
- b) curing the uncured addition-cure silicone elastomer in the mold to provide a ring body comprising first and second channels adapted to receive first and second drug-containing cores;
- c) removing the ring body from the mold;
- and
- d) inserting the first drug-containing core into the first channel and inserting the second drug-containing core into the second channel, wherein the first and second drug-containing cores contain, in total, approximately 103 mg of segesterone acetate, and approximately 17.4 mg of ethinyl estradiol and wherein the first drug-containing core contains segesterone acetate and the second drug-containing core contains segesterone acetate and ethinyl estradiol.
2 more elements
Dependencies are inferred from the claim text.