Back to results
US 12,702,587 B2Granted
Ophthalmic device
AssigneeaVISI Ltd.
InventorNir Betser
Life of this patent
Estimating the term…
Abstract
An ophthalmic device including: a body having: a posterior surface; an anterior surface; wherein a size of the body, a shape of the posterior surface, and a shape of the anterior surface configures the device to reside on a bulbar conjunctiva of an eye.
Claims27
An ophthalmic device comprising:
- a body having:
- a posterior surface;
- an anterior surface;
- wherein a size of the body, a shape of the posterior surface, and a shape of the anterior surface configures the device to reside on a bulbar conjunctiva of an eye;
- wherein the device is flexible and has a Young modulus of from 0.3 to 1.5 MPa;
- wherein the body of the ophthalmic device is configured to reside on the bulbar conjunctiva of the eye for a period of less than 24 hours from administration.
3 more elements
An ophthalmic device comprising:
- a body having:
- a posterior surface;
- and
- an anterior surface;
- wherein the body comprises therapeutic material and is configured to elute the therapeutic material into the eye, wherein a size of the body, a shape of the posterior surface, and a shape of the anterior surface configure the device to reside on a bulbar conjunctiva of an eye, between the cornea and the conjunctiva of a lower fornix, wherein an entirety of the device, prior to use in the eye, is flexible and has a Young's modulus of from 0.3 to 1.5 MPa;
- wherein the body of the device is configured to reside on the bulbar conjunctiva of the eye and elute the therapeutic material into the eye for a period of less than about 24 hours from administration.
3 more elements
A method of treating a patient suffering from an ophthalmic condition, the method comprising:
- applying an ophthalmic device, without pre-hydrating the device, to a bulbar conjunctiva of the patient's eye in such a way as to allow the ophthalmic device to reside on the bulbar conjunctiva for a residence time of at least 15 minutes, with no portion of the device residing above the patient's lower eyelid, the device comprising a body having a posterior surface and an anterior surface, the body comprising therapeutic material which is eluted into the patient's eye to treat the ophthalmic condition, the device undergoing hydration in situ by the patient's tear fluid, wherein the hydration causes the device to expand by at least 10% but no more than 50% along one dimension;
- wherein the residence time is no more than 24 hours;
- and
- wherein the device is flexible and has a Young modulus of from 0.3 to 1.5 MPa.
1 more element
A method of treating a patient suffering from an ophthalmic condition, the method comprising:
- applying an ophthalmic device to a bulbar conjunctiva of the patient's eye in such a way as to allow the ophthalmic device to reside in the eye of the patient for a residence time of up to 24 hours, the device comprising a body having a posterior surface and an anterior surface, the body comprising therapeutic material which is eluted into the patient's eye to treat the ophthalmic condition;
- and
- at the conclusion of the residence time, expelling or removing the device from the bulbar conjunctiva;
- wherein the device is flexible and has a Young modulus of from 0.3 to 1.5 MPa.
1 more element
A method of treating a patient suffering from an ophthalmic condition, the method comprising:
- covering a portion of a bulbar conjunctiva with an ophthalmic device, causing the ophthalmic device to adhere to the bulbar conjunctiva through suction provided by surface tension forces generated by a difference in curvature between a posterior surface of the ophthalmic device and the bulbar conjunctiva;
- leaving the ophthalmic device on the bulbar conjunctiva for a residence time period;
- and
- degrading the device during the residence time period by exposing the device to tear fluid and movement of the patient's eyeball and lower eyelid;
- wherein the degrading reduces adherence of the device to the bulbar conjunctiva;
- wherein the residence time is no more than 24 hours;
- wherein the device is flexible and has a Young modulus of from 0.3 to 1.5 MPa.
4 more elements
A method of treating a patient suffering from an ophthalmic condition, the method comprising:
- covering a portion of a bulbar conjunctiva under the lower eyelid with an ophthalmic device,
- causing the ophthalmic device to adhere to the bulbar conjunctiva through suction provided by surface tension forces generated by a difference in curvature between a posterior surface of the ophthalmic device and the bulbar conjunctiva;
- and
- allowing the device to elute a therapeutic material into the patient's eye to treat the ophthalmic condition;
- wherein the device is allowed to reside in the patient's eye for a time period of not more than 24 hours;
- and
- wherein the device is flexible and has a Young modulus of from 0.3 to 1.5 MPa.
4 more elements
Dependencies are inferred from the claim text.