Devices, methods, and compositions for thermal acceleration and drug delivery

A thermally-activated combined treatment composition, comprising:

• a therapeutic agent;
• and
• a thermal accelerant configured to:
• enhance ablation treatment;
• be impregnated with the therapeutic agent;
• and
• elute the therapeutic agent after exposure to energy from an energy source, wherein:
• the combined treatment composition is thermally activated by exposure to energy from an energy source;
• and
• after the thermal accelerant is exposed to the energy from the energy source:
• the thermal accelerant is configured to become coagulated and becomes coupled with the ablated tissue;
• and
• the thermal accelerant is configured to begin to elute a portion of therapeutic agent.

A thermally-activated combined treatment composition, comprising:

• a therapeutic agent;
• and
• a thermal accelerant configured to:
• enhance ablation treatment;
• be impregnated with the therapeutic agent;
• and
• elute the therapeutic agent after exposure to energy from an energy source, wherein:
• the combined treatment composition is thermally activated by exposure to energy from an energy source;
• and
• the thermal accelerant comprises:
• a carrier comprising an albumin;
• an ionic component comprising at least one chaotrope;
• and
• an imaging component.