Brain image processing

A system comprising:

• at least one processor;
• and
• memory storing computer-executable instructions that, when executed by the at least one processor, cause the at least one processor to:
• transform, into a common space, a plurality of reference points obtained from at least one image of a reference brain in a first space wherein each of the reference points comprise a plurality of surface vertices, each associated with a vertex index;
• transform, into the common space, a plurality of test points obtained from at least one image of a test brain in a second space wherein each of the test points comprise a plurality of surface vertices, each associated with a surface index;
• determine a position of each of the transformed reference points and each of the transformed test points in the common space;
• calculate a displacement of each of the transformed test points relative to each of the transformed reference points based on the determined positions;
• determine a correspondence between one of the transformed test points and a given transformed reference point based on the calculated displacements, wherein determining the correspondence between one of the transformed test points and the given transformed reference point further comprises determining the transformed test point having a minimum displacement relative to the given transformed reference point;
• determine a corresponding test point in the second space to a given reference point in the first space based on the determined correspondence,
• obtain one or more reference values of one or more measured parameters at each of the plurality of reference points;
• and
• obtain corresponding one or more test values of one or more measured parameters at each of the plurality of test points, wherein the one or more measured parameters comprises at least one of a principal diffusion component-based parameter, a minicolumn-based parameter, or a diffusion-based parameter.

A computer-implemented method comprising:

• transforming, into a common space, a plurality of reference points obtained from at least one image of a reference brain in a first space, wherein each of the reference points are associated with a relative reference position in the first space and comprise a plurality of surface vertices each associated with a vertex index;
• transforming, into the common space, a plurality of test points obtained from at least one image of a test brain in a second space, wherein each of the test points are associated with a relative test position in the second space and comprise a plurality of test vertices each associated with a test index;
• determining a position of each of the transformed reference points and each of the transformed test points in the common space;
• calculating a displacement of each of the transformed test points relative to each of the transformed reference points based on the determined positions;
• determining a correspondence between one of the transformed test points and a given transformed reference point based on the calculated displacements;
• determining a corresponding test point in the second space to a given reference point in the first space based on the determined correspondence, wherein the relative test position and the relative reference position are substantially equivalent points in the test brain and the reference brain;
• obtaining one or more reference values of one or more measured parameters at each of the plurality of reference points;
• obtaining corresponding one or more test values of one or more measured parameters at each of the plurality of test points;
• comparing the one or more reference values at the given reference point to the one or more test values obtained at the corresponding test point;
• and
• obtaining an indication of a prognosis of at least one disorder in the test brain and/or an indication of a presence of at least one disorder in the test brain based on the comparison of the one or more reference values at the given reference point to the one or more test values obtained at the corresponding test point.