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US 12,699,155 B2Granted
Continuous three-dimensional imaging for magnetic resonance elastography
AssigneeMayo Foundation for Medical Education and Research
InventorsArvin Forghanian-Arani, Joshua D. Trzasko, Yi Sui, Philip A. Araoz, Richard L. Ehman, John Huston, III
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Abstract
Described here are systems and methods for a robust magnetic resonance elastography (“MRE”) imaging platform for rapid dynamic 3D MRE imaging. The imaging platform includes an MRE pulse sequence and advanced image reconstruction framework that work synergistically in order to greatly expand the domains where MRE can be deployed successfully.
Claims14
A method for generating a mechanical property map using a magnetic resonance imaging (MRI) system, the method comprising:
- (a) acquiring data from a subject using the MRI system while a vibratory stimulus is provided to the subject in order to induce motion within a tissue of the subject, wherein:
- the data are acquired using a pulse sequence that samples k-space in a plurality of planes using an echo planar readout,
- each plane is radially rotated about a phase encoding axis in successive repetition time periods of the pulse sequence, and
- the pulse sequence includes motion encoding gradients that are generated before each echo planar readout in order to encode the motion within the tissue into an image phase of the data;
- wherein the data are acquired with uniform undersampling in a through-plane dimension;
- (b) reconstructing a plurality of images from the data while accounting for the uniform undersampling in the through-plane dimension, wherein the reconstructed images are indicative of the image phase into which the motion within the tissue has been encoded;
- and
- (c) generating a mechanical property map from the reconstructed images.
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