Back to results
US 12,699,095 B2Granted
Cancer diagnosis using Ki-67
AssigneeQuest Diagnostics Investments Incorporated
InventorsJean Marie Bruey, Maher Albitar
Life of this patent
Estimating the term…
Abstract
The present invention provides methods and compositions for detection, diagnosis, prognosis, monitoring treatment and monitoring progression of cancer by detecting the level of Ki-67 protein in an individual.
Claims13
A method comprising:
- (a) obtaining a plasma sample from a subject suspected of having lymphoma;
- (b) contacting the plasma sample with an agent that binds to a Ki-67 protein that is detectable in the plasma sample, wherein the plasma sample contains less than about 1% (w/w) whole cellular material;
- and
- (c) detecting a level of Ki-67 protein in the plasma sample by performing an immunoassay, wherein the level of Ki-67 protein is above about 1500 U/mL.
1 more element
Dependencies are inferred from the claim text.