Back to results
US 12,698,254 B2Granted
Crystalline solids of 3-palmitoyl-amido-1,2-propanediol and 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane and methods of making and using the same
AssigneeGeron Corporation
InventorJennifer E. Albaneze-Walker
Life of this patent
Estimating the term…
Abstract
Aspects of the disclosure include crystalline solids of 3-palmitoyl-amido-1,2-propanediol and 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane. Methods for preparing the crystalline solids of 3-palmitoyl-amido-1,2-propanediol and single crystals of 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane are also provided. Methods for preparing a 3-palmitoyl-amido-2-hydroxy-1-dimethoxytriphenylmethylether-propane from a crystalline solid of 3-palmitoyl-amido-1,2-propanediol are also described.
Claims4
A crystalline solid of a compound of Formula II
- wherein DMTr is dimethoxytriphenylmethyl;
- each unit cell in the crystalline solid comprises conformer A and conformer B of the compound of Formula II;
- and conformer A has the atomic coordinates and equivalent isotropic displacement parameters:
- O1A
- 0.8579(3)
- 0.7210(3)
- 0.75600(12)
- 0.0408(9)
- N1A
- 0.0410(5)
- 0.8405(4)
- 0.75844(15)
- 0.0504(13).
10 more elements
Dependencies are inferred from the claim text.