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US 12,697,386 B2Granted
Nucleic acid antibody constructs for use against Ebola virus
AssigneeThe Wistar Institute of Anatomy and Biology
InventorDavid Weiner
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Abstract
Disclosed herein is a composition including a recombinant nucleic acid sequence that encodes an antibody to an Ebola viral antigen. Also disclosed herein is a method of generating a synthetic antibody in a subject by administering the composition to the subject. The disclosure also provides a method of preventing and/or treating an Ebola virus infection in a subject using said composition and method of generation.
Claims12
A composition comprising a first, a second, a third, a fourth, a fifth, and a sixth nucleotide sequence,
- wherein the first nucleotide sequence encodes SEQ ID NO:
- 1;
- wherein the second nucleotide sequence encodes SEQ ID NO:
- 3;
- wherein the third nucleotide sequence encodes SEQ ID NO:
- 5;
- wherein the fourth nucleotide sequence encodes SEQ ID NO:
- 7;
- wherein the fifth nucleotide sequence encodes SEQ ID NO:
- 9;
- and
- wherein the sixth nucleotide sequence encodes SEQ ID NO:
- 11.
10 more elements
Dependencies are inferred from the claim text.