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AssigneeTennor Therapeutics (Suzhou) Limited
InventorsZhenkun Ma, Yue Xu, Yu Liu, Huan Wang, Shijie He, Yan Zhang, Xiangyi Xu
Estimating the term…
The present application relates to a pharmaceutical composition comprising sulbactam or a pharmaceutically acceptable salt thereof, avibactam or a pharmaceutically acceptable salt thereof, and optionally a pharmaceutically acceptable carrier, wherein unit dose ratio of said sulbactam or the pharmaceutically acceptable salt thereof and said avibactam or the pharmaceutically acceptable salt thereof is about 8:1 to about 4:1, unit dose of said sulbactam or the pharmaceutically acceptable salt thereof is about 1 g-4 g, and unit dose of said avibactam or the pharmaceutically acceptable salt thereof is about 0.125 g-1 g. The present application also relates to methods of treating bacterial infections using said pharmaceutical composition.
A pharmaceutical composition comprising sulbactam or a pharmaceutically acceptable salt thereof and avibactam or a pharmaceutically acceptable salt thereof, and optionally a pharmaceutically acceptable carrier, wherein unit dose ratio of said sulbactam or the pharmaceutically acceptable salt thereof to said avibactam or the pharmaceutically acceptable salt thereof is about 8:1 to about 4:1, unit dose of said sulbactam or the pharmaceutically acceptable salt thereof is about 1 g-4 g, and unit dose of said avibactam or the pharmaceutically acceptable salt thereof is about 0.125 g-1 g.
A method for preventing, treating and/or alleviating bacterial infections, wherein said method comprises administering to a patient in need thereof sulbactam or a pharmaceutically acceptable salt thereof and avibactam or a pharmaceutically acceptable salt thereof, ratio of administration dosage of said sulbactam or the pharmaceutically acceptable salt thereof to said avibactam or the pharmaceutically acceptable salt thereof is about 8:1 to about 4:1 and the administration dosage of said sulbactam or the pharmaceutically acceptable salt thereof is about 4 g-12 g/day, and the administration dosage of said avibactam or the pharmaceutically acceptable salt thereof is about 0.5 g-3 g/day.
Dependencies are inferred from the claim text.