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US 12,697,323 B2Granted
Implantable isoxazoline pharmaceutical compositions and uses thereof
AssigneeIntervet Inc.
InventorsKeith Freehauf, Anagha Avinash Bhakay
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Abstract
An implant for the control of parasites in livestock comprising an isoxazoline compound of Formula (I) or salt or solvate thereof, wherein the implant comprises one or more pellets each of which comprises the isoxaxoline compound and a pharmaceutically acceptable excipient and a method of preventing or treating a parasite infestation using the same.
Claims9
A method of treating a parasite infestation in livestock animals comprising administering an implant to animals in need thereof wherein the implant comprises
- one or more immediate release pellets and one or more delayed release pellets, wherein the ratio of the immediate release pellets and the delayed release pellets is between 1:10 and 10:1 and wherein
- a) the immediate release pellets comprise
- i) fluralaner
- ii) diluent;
- iii) binder and
- iv) micronized intragranular poloxamer, and
- b) the delayed release pellets comprise
- i) fluralaner
- ii) diluent, and
- iii) binder;
- wherein the delayed release pellets are coated with a biodegradable polymer.
8 more elements
Dependencies are inferred from the claim text.