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US 12,697,298 B2Granted
Optimized synthetic consensus immunogenic compositions targeting fibroblast activation protein
AssigneesThe Trustees of the University of Pennsylvania, The Wistar Institute of Anatomy and Biology
InventorsDavid Weiner, Elizabeth Duperret
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Abstract
Provided herein is an immunogenic composition comprising a synthetic consensus FAP antigen. Also disclosed herein is a method of treating or preventing a tumor associated pathology in a subject in need thereof, by administering the immunogenic composition to the subject.
Claims9
An isolated nucleic acid molecule encoding a single polypeptide, wherein the single polypeptide comprises the amino acid sequence of SEQ ID NO:4.
An isolated peptide consisting of the amino acid sequence of SEQ ID NO:4.
Dependencies are inferred from the claim text.