Magnetomotive probe and method of use thereof
AssigneeNanoEcho AB
InventorsMaria Evertsson, Tomas Jansson
Life of this patent
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Abstract
A magnetomotive imaging probe device and method is described. The probe device includes a housing having an outer surface and an inner cavity; a magnet; a sensing device configured to detect distance, movement, or magnetic material. The magnet is arranged in the inner cavity of the housing and the sensing device on the outer surface of the housing, and the magnet is arranged to generate a time-varying magnetic field at an imaging plane of the sensing device. The magnet is intended to move magnetic nanoparticles in tissue such that a movement can be detected with the sensing device (ultrasound, optical or other). The detected motion infers the presence of magnetic material (nanoparticles).
Claims20
A magnetomotive imaging probe device, comprising:
- a housing having an outer surface and an inner cavity;
- a magnet;
- and
- a sensing device configured to detect distance, movement, or magnetic material;
- wherein the magnet is arranged in the inner cavity of the housing and the sensing device is arranged on the outer surface of the housing, wherein a distance between the magnet and the sensing device is defined mainly by the thickness of the housing at the position of the sensing device and/or a distance between an inner surface of the housing and the magnet, wherein the magnet is arranged to generate a time-varying magnetic field at an imaging plane of the sensing device, and wherein the imaging plane extends outside of the housing.
A method of magnetomotive imaging, comprising:
- introducing magnetic particles in tissue of a subject to be examined;
- obtaining a time varying magnetic field using a magnet arranged in a cavity of a housing of a probe, the time varying magnetic field causing the magnetic particles to oscillate and/or move in an imaging plane of a sensing device arranged on an outer surface of the housing, wherein a distance between the magnet and the sensing device is defined mainly by the thickness of the housing at the position of the sensing device and/or a distance between an inner surface of the housing and the magnet, and wherein the imaging plane is outside of the housing;
- imaging the oscillation and/or movement of the particles using the sensing device;
- and
- analyzing the oscillation and/or movement of the particles to determine a distribution of the magnetic particles.
A magnetomotive imaging probe device comprising:
- a housing having an outer surface and an inner cavity;
- a magnet;
- and
- a sensing device configured to detect distance, movement, or magnetic material;
- wherein the magnet is arranged in the inner cavity of the housing and the sensing device is arranged on the outer surface of the housing, wherein the magnet is arranged to generate a time-varying magnetic field at an imaging plane of the sensing device, and wherein the housing has an elongated shape that is configured for transrectal or transvaginal use.
Dependencies are inferred from the claim text.