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US 12,693,303 B2Granted
Substance dispense system for biological sample analysis instrument
AssigneeBeckman Coulter, Inc.
InventorsKiyotaka Kubota, Atsushi Matsushita, Takayuki Mizutani, Hitoshi Narita, Kazuki Umebara
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Abstract
A substance dispense system is provided for a biological sample analysis instrument. The substance dispense system can operate to prepare a fluidic substance, such as a sample, using a dispense tip in different operational modes based on the volume of the fluid substance to be prepared. The substance dispense system thereby improves accuracy and/or precision in pipetting with the dispense tip.
Claims22
A method for preparing a liquid substance for evaluation, the method comprising:
- aspirating a first volume of the liquid substance from a first vessel to a dispense tip;
- and
- dispensing a second volume of the liquid substance from the dispense tip to a second vessel by:
- lowering the dispense tip into the second vessel at a first height, the first height configured such that a distal end of the dispense tip remains above a liquid surface level in the second vessel;
- dispensing part of the second volume of the liquid substance from the dispense tip to the second vessel at the first height such that the dispense tip retains a rest of the second volume of the liquid substance therein;
- lowering the dispense tip to a second height, the second height configured such that the distal end of the dispense tip touches the liquid surface level in the second vessel;
- and
- dispensing the rest of the second volume of the liquid substance from the dispense tip to the second vessel at the second height.
5 more elements
Dependencies are inferred from the claim text.