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US 12,693,295 B2Granted
Methods for inkjet printing objects for microfluidic devices
AssigneeUniversity of Kansas
InventorYong Zeng
Life of this patent
Estimating the term…
Abstract
Provided herein are methods for inkjet printing objects, including objects which may be used as elements of microfluidic devices. The microfluidic devices incorporating the elements are also provided. Such microfluidic devices include those configured to quantify the expression and activity of exosomal matrix metalloprotease, MMP14. These microfluidic devices may be used in methods of monitoring breast cancer in patients having breast cancer.
Claims14
A method for inkjet printing an object, the method comprising:
- (a) depositing a first droplet of an ink composition comprising particles dispersed in a liquid phase onto a surface of a substrate at first location and evaporating the liquid phase from the deposited first droplet to form a first ring structure on the surface at the first location, the first ring structure comprising the particles;
- (b) depositing a second droplet of the ink composition onto the surface at a second location laterally offset from the first location by a droplet spacing value and evaporating the liquid phase from the deposited second droplet to form a second ring structure on the surface at the second location, the second ring structure comprising the particles, wherein the second ring structure is offset from, and partially overlap s with, the first ring structure;
- and
- (c) repeating step (b) one or more additional times with one or more additional droplets to form a first layer of offset and partially overlapping ring structures on the surface of the substrate, the first layer comprising the first and second ring structures and one or more additional ring structures formed from the one or more additional droplets, thereby forming an object.
1 more element
Dependencies are inferred from the claim text.