Back to results
US 12,693,287 B2Granted
Disposable hemolysis sensor
AssigneeInstrumentation Laboratory Company
InventorsBrian Joseph Bosy, Josef Kerimo
Life of this patent
Estimating the term…
Abstract
An apparatus for measuring hemolysis in a cartridge based automated blood analyzer is described. The apparatus allows hemolysis testing to be performed on a sample which is presented as a whole blood sample for other testing by the cartridge based automated blood analyzer. A disposable module is configured for optically analyzing one or more plasma analytes in a flow cell while red blood cells are acoustically separated from plasma in the flow cell.
Claims19
A sensor module comprising:
- a flow cell for holding a blood sample, the flow cell comprising a lumen and at least one wall surrounding the lumen;
- an apparatus that is configured to be installed in, and removed from, an instrument configured to perform one or more analyses on a blood sample, wherein the flow cell is secured in a fixed position within the apparatus, the apparatus comprising an inlet port and an outlet port that are configured so that the sensor module can be installed in-line with a structure holding blood contained within the instrument to provide the blood sample from the instrument to the flow cell;
- and
- from the instrument, respectively, the acoustic transducer being responsive to an electrical signal to generate an acoustic transducer secured between parts of the apparatus to be proximate to the flow cell such that the acoustic transducer is installed in and removed from the instrument when the apparatus and the flow cell are installed in and removed acoustic force that causes separation of blood cells from plasma in the blood sample such that plasma is localized in the lumen of the flow cell and blood cells are localized next to the plasma localized in the lumen between the at least one wall of the flow cell and the plasma localized in the lumen;
- wherein, when the sensor module is installed in-line with the structure of the instrument, the flow cell is aligned to an optical path to an optical device configured to capture information at least from the plasma localized in the lumen of the flow cell, the one or more analyses being based on the information.
2 more elements
Dependencies are inferred from the claim text.