In vitro diagnosis method for periodontal diseases, and Pg bacterium detection method
AssigneeNational Institute for Materials Science
InventorsAkihiro Okamoto, Divya Naradasu
Life of this patent
Estimating the term…
Abstract
The in vitro diagnostic method for periodontal disease of the present invention includes bringing a sample derived from an oral cavity of a subject into contact with an electrode to perform electrochemical measurement in the presence of a glucogenic amino acid and an electron mediator under an anaerobic environment and providing information for judging that periodontal disease is progressing in the oral cavity of the subject when current generation is detected as a result of the electrochemical measurement. According to the in vitro diagnostic method for periodontal disease of the present invention, it is possible to provide information for judging the progress of periodontal disease by simple operation.
Claims20
An in vitro diagnostic method for periodontal disease, comprising:
- bringing a sample derived from an oral cavity of a subject into contact with an electrode to perform electrochemical measurement in the presence of a glucogenic amino acid and an electron mediator under an anaerobic environment;
- and
- providing information for judging that periodontal disease is progressing in the oral cavity of the subject when a current generated by anaerobic metabolism of periodontopathogenic bacteria is detected as a result of the electrochemical measurement.
A Porphyromonas gingivalis (Pg) bacterium detection method comprising:
- bringing a sample into contact with an electrode to perform electrochemical measurement in the presence of a glucogenic amino acid and 2-hydroxy-1,4-naphthoquinone under an anaerobic environment;
- and
- providing information for judging that Pg is contained in the sample when current generation is detected as a result of the electrochemical measurement.
Dependencies are inferred from the claim text.