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US 12,692,260 B2Granted
Compound having inhibitory activity against O-glusacase and use thereof
AssigneeMedifron DBT Co., Ltd.
InventorsHee Kim, Hee Jin Ha, Hye Min Ju, Ki Sun Roh, Jae Hong Im, Jin Mi Kang, Minyoung Lee
Life of this patent
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Abstract
The present invention relates to a novel compound having inhibitory activity against O-GlcNAcase and a use thereof.
Claims12
A compound represented by Chemical Formula 1 below or a pharmaceutical salt thereof:
- wherein,
- D is a ring selected from the group consisting of substitutable C3 to C10 cycloalkyl, substitutable 5-membered unsaturated or aromatic ring, substitutable 6-membered unsaturated or aromatic ring, substitutable 5-membered unsaturated or aromatic heterocyclic ring, and substitutable 6-membered unsaturated or aromatic heterocyclic ring, or a polycyclic ring in which two or more rings selected from the group are fused,
- X1 is C, N, O or S,
- X2 is N or O,
- R1, R2 and R3 are each independently hydrogen or C1 to C5 alkyl,
- L is a direct bond or a C1 to C12 alkylene group, and
- n is an integer of 0 to 3.
4 more elements
Dependencies are inferred from the claim text.