Compound having anti-tumor activity and use thereof

A compound represented by formula (III), or stereoisomer, geometric isomer, tautomer, pharmaceutical salt, prodrug, hydrate, solvate, or isotope-labeled analogue thereof:

• wherein,
• R16 is selected from hydrogen, deuterium, halogen, hydroxy, mercapto, amino, cyano, —R9, —OR9, —SR9, —NH(R9) and —N(R9)(R10);
• at each occurrence, R9 and R10 are each independently selected from C1-6alkyl and C3-6cycloalkyl, or R9 and R10 together with the N atom to which they are connected form 4-6 membered heterocyclyl;
• R11 is selected from C6-8aryl and 5-6 membered heteroaryl, and the aryl or heteroaryl is optionally substituted by one or more of halogen, C1-6alkyl, and trifluoromethyl;
• the heterocyclyl or heteroaryl contains 1, 2 or 3 heteroatoms, which are each independently selected from N, O and S.