Indole carboxamide compound, preparation therefor and use thereof

An indole carboxamide compound represented by formula (I) or pharmaceutically acceptable salts thereof:

• wherein:
• R1 is selected from a group consisting of hydrogen atom, hydroxyl, aldehyde group, halogen, guanidino, C1-6 alkyl, C2-6 alkenyl, C2-6 alkynyl, 6- to 14-membered aryl, 5- to 6-membered heteroaryl, C1-6 alkyloxy, 6- to 14-membered aryloxy, —OCH2-6- to 14-membered aryl, —CF3, —OCHF2, —OCF3, —CN, nitro group, carboxyl, —C(O)O—C1-6 alkyl, —C(O)N—C1-6 alkyl, amino group, —NHC(O)—C1-6 alkyl, —S—C1-6 alkyl, —SO—C1-6 alkyl, —SO2-C1-6 alkyl or a heterocyclic ring containing 1~4 heteroatoms selected from N, O and S;
• the C1-6 alkyl, the 6- to 14-membered aryl or the 5- to 6-membered heteroaryl are optionally substituted with 1 to 5 substituents selected from a group consisting of hydroxyl, nitro group, sulfonic group, halogen, cyano, trifluoromethyl, difluoromethoxy or trifluoromethoxy;
• and the 5- to 6-membered heteroaryl optionally contain 1 to 6 heteroatoms selected N, O and S;
• R2 is selected from a group consisting of hydrogen atom, C1-10 alkyl, 6- to 14-membered aryl, 5- to 6-membered heteroaryl, amino group, substituted amino group, amidino group or guanidino;
• wherein the C1-10 alkyl, the 6- to 14-membered aryl or the 5- to 6-membered heteroaryl are optionally substituted with 1 to 2 substituents selected from a group consisting of hydroxyl, nitro group, halogen, cyano, trifluoromethyl, 6- to 8-membered aryl, trifluoromethoxy or difluoromethoxy;
• and the 5- to 6-membered heteroaryl optionally contain 1 to 6 heteroatoms selected from N, O and S.