Devices for improving sample preparation and processing
AssigneeIllumina, Inc.
InventorsYi Xue, Huicheng Wang, Sepehr Kiani, Corey Alicchio
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Abstract
The invention provides devices for improving assay protocol compliance, reproducibility, and sensitivity. In particular, the devices of the present invention are tailored to certain single-cell sequencing assays, including single-cell RNA sequencing assays that utilize pre-templated instant partitions (PIPs) templates, wherein such devices hold tubes stationary while performing sample preparation, provide reproducible volume removal from tubes, allow for improved magnetic separation of analytes from buffers, and provide reproducible centrifugation of tubes.
Claims20
A vortex adapter configured for use with a vortex mixer, said adapter comprising:
- a base comprising a proximal portion releasably couplable to a hub of a vortex mixer;
- and
- a tube holder releasably mounted to a distal portion of the base and comprising a plurality of apertures for receiving a plurality of tubes, respectively, wherein said tube holder is movable between a fixed first position in which the tube holder is releasably mounted to the distal portion of the base such that each of said apertures is oriented in a vertical direction relative to the base and a second fixed position in which the tube holder is releasably mounted to the distal portion of the base such that each of said apertures is oriented in a horizontal direction relative to the base.
Dependencies are inferred from the claim text.