Intranasal delivery devices and methods of use
AssigneeRocket Science Health Corp.
InventorsKenneth Irving, James Jackson, Alec Lillis, Manu Sharma
Life of this patent
Estimating the term…
Abstract
The present disclosure describes devices for intranasal drug delivery to targeted regions and sub-regions of a nasal cavity of a subject, including turbinates. The devices may have a housing with a dispensing element, and a positioning or trigger element coupled to the housing that positions the dispensing element within a nasal channel and limits its depth of insertion. The dispensing element may comprise a side opening for dispensing a composition. Devices of the present disclosure may provide a convenient and effective way to deliver compositions intranasally to the targeted regions and sub-regions while limiting off-target delivery.
Claims15
A device for intranasal delivery to a subject, the device comprising:
- (a) a housing defining an insertable portion configured for insertion into a nasal channel of the subject, the insertable portion comprising a distal end, and a proximal end;
- and
- (b) a subject engaging portion coupled to the proximal end of the insertable portion, the subject engaging portion comprises a U shape and is configured to engage a columella region of the subject by simultaneously contacting a downward facing lateral face of the columella region, a leftward facing lateral face of the columella region, and a rightward facing lateral face of the columella region, thereby seating the insertable portion such that the distal end of the insertable portion is positioned within an ejection zone of the nasal channel of the subject, wherein the ejection zone is:
- (i) 0 mm to 30 mm superior to a horizontal line that intersects an anterior aspect of an internal nasal valve, and
- (ii) 0 mm to 20 mm anterior to an inclined line that intersects an anterior aspect of a middle turbinate and a posterior aspect of a vestibule,
- wherein the insertable portion comprises a dispensing element for delivery of a composition to a region or sub-region of the nasal channel of the subject, wherein the dispensing element comprises a side opening.
Dependencies are inferred from the claim text.